2-Phenyl-2-propanol is an important raw material for the synthesis of diisopropylbenzene peroxide (DCP), which belongs to alcohol derivatives.

Characteristics

2-Phenyl-2-propanol is a white to pale yellow, odorless solid. It is flammable but difficult to ignite under normal conditions, and almost insoluble in water.

Applications

2-Phenyl-2-propanol can be used in organic synthesis, as well as in the fields of pesticides, pharmaceuticals, and dyes as reactants or intermediates.

2-Phenyl-2-propanol is the main metabolite of diisopropylbenzene, making it a biomarker for diisopropylbenzene.

Reasons for restriction

Currently, there are no legal regulations on this chemical in finished products, but multiple brands' RSL and AFIRM RSL list it as a restricted chemical.

The German Federal Institute for Risk Assessment (BfR) comments that 2-Phenyl-2-propanol may cause allergic reactions.

Synthesis method

One industrial method for synthesizing 2-Phenyl-2-propanol involves the reaction of water-soluble sulfide MxS with diisopropylbenzene peroxide, where M represents H, Li, Na, K, Ca, Mg, or NH4 +. The amount of MxS used is 200% of the theoretical amount determined by the reaction equation, with a reaction temperature of 0-150°C and a reaction time of 0.5-8 hours. After the reaction, the layers are separated, the lower aqueous phase is removed, and the organic phase is washed with water until the pH of the water phase is 6-8 to obtain the product.