（20-50wt%）氢氧化钯/碳 是什么意思? < >在客户给的工艺中有个 催化剂 是 （20-50wt%） 氢氧化钯/碳 20-50wt%含量是什么意思？20%是指钯与碳的质量比，50%是干重？</P> < >另看到两篇文献可以参考一下</P> < >Synthesis of (R)-N-[3-[2-[2-(2-tert-butyl-3-methyl-1H-indol-6-yloxy)ethylamino]-1-hydroxyethyl]phenyl]methanesulfonamide hydrochloride<BR>The compound (100 mg; obtained in the above step C) was dissolved in a mixed solvent of THF (1 mL) and methanol (1 mL), to which <FONT color=#ff0000>20% palladium hydroxide/carbon powder (40 mg, 50% moisture)</FONT> was added. The atmosphere in the system was replaced with hydrogen, followed by stirring at room temperature for 20 hours. The reaction mixture was filtered and the filtrate was placed under reduced pressure to distill the solvent off. To the residue, ethanolic 0.1 N hydrochloric acid (16 mL) was added. After stirring at room temperature for 10 minutes, the solvent was distilled off. Ether was added to the residue. The deposited crystal was collected by filtration and dried to yield the title compound (76.6 mg).</P> < >Synthesis of Tetraacetyldibenzylhexaazaisowurtzitane <BR>67 ml of dimethylformamide (DMF), 17 ml of acetic anhydride, 0.23 g (1.46 mmol) of bromobenzene, 20.8 g (29.4 mmol) of hexabenzylhexaazaisowurtzitane and 1.15 g of <FONT color=#ff0000>palladium hydroxide-on-charcoal (moisture: 50%, level of palladium in the dry material: 5%)</FONT> are introduced, at room temperature (15-20° C.), into a 250 ml jacketed reactor equipped with a magnetic stirrer, a water-cooled reflux condenser and an introduction pipe equipped with a sinter for the introduction of hydrogen. After purging the equipment with an inert gas, the reaction mixture is brought from room temperature to 55° C. over 3 h, while introducing hydrogen into the mixture and while maintaining its pressure in the reactor at between 1.13×10 5 Pa and 1.25×10 5 Pa, and this temperature is then maintained for 2 h. </P>查看更多6个回答 . 1人已关注
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