请问文献中的这个反应我重复的话能否用固体光气代替光气 ...？ < >文献如下：Synthesis of Acetylene-Terminated PEG 2000 (Acetylene PEG,<BR>2). PEG diol 2000 (10 g, [-OH] ) 10 mmol) was dissolved in dry<BR>toluene, refluxed, and dried in a vacuum to remove water. Phosgene<BR>solution (15 mL, 20% in toluene) was then added into the dried PEG<BR>with stirring. The reaction was allowed to proceed overnight in a fume<BR>hood. The excess phosgene was removed in vacuum. DCM (20 mL)<BR>was used to dissolve the viscous residue. Propargyl amine (1.65 g, 30<BR>mmol) was then added into the solution. The reaction was allowed to<BR>proceed for 7-8 h at room temperature. The product was precipitated<BR>into diethyl ether three times and purified by a LH-20 column. Yield:<BR>83.3%. 1H NMR (D2O) ä (ppm): 4.23 (t, PEG, -CH2-), 3.89 (s,<BR>propargyl amide, -CH2-), 3.68 (m, PEG, -CH2-). 13C NMR (CDCl3)<BR>ä (ppm): 155.80, 79.74, 71.24, 70.32, 69.22, 64.01, 30.44. To confirm<BR>the 100% derivatization of PEG diol into acetylene-terminated PEG,<BR>the product was also analyzed by 1H NMR (CDCl3). No -OH signal<BR>(ä ) 2.63 ppm) was detected.</P> < >希望用过 光气 的同学解答下，还有如果换成 固体光气 的话怎么操作呢？</P> < >谢谢</P>查看更多2个回答 . 2人已关注
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