mediated 如何理解(VA的MSDS)? 关于 Vinyl acetate (VA)-- 乙酸乙烯酯 的毒理学资料: Following inhalation and oral exposure VA is rapidly hydrolyzed by carboxylesterases leading to the formation of acetic acid and acetaldehyde which is further converted into acetic acid in the presence of aldehyde dehydrogenases. VA data support the idea that VA genotoxicity is mediated by acetaldehyde, validated in observations of increasing concentrations of acetaldehyde. While these data suggest that VA might pose a cancer risk for humans via inhalation or oral route, carcinogenicity mediated via this secondary mechanism appears relevant above threshold concentrations. 暂定为6 楼。 查看更多18个回答 . 2人已关注