硝基还原，产物得不到白色固体？ quote: 以下是引用 shan 在2009-6-10 22:16:00的发言： 类似的： example text 3-amino-4-dimethylamino-1-phenyl-1h-pyridin-2-one, compound 4. 4-dimethylamino-3-nitro-1-phenyl-1h-pyridin-2-one (1.0 g, 3.86 mmol) was dissolved in dioxane/water/nh4oh (1:1:1, 10 ml). a solution of na2s2o4 (2.01 g, 11.58 mmol) in water (5 ml) was added. the reaction mixture was allowed to stir for 4 h at room temperature, then the mixture was filtered through celite, washed with dichloromethane, and purified by flash chromatography on silica gel with hexane/ethylacetate (2:1) to provide 0.75 g (85percent) of the product as white solid. 这个化合物我合成过.是可以得到类白色的固体物质.用zn+meoh+hcl+nh4cl体系!!! 但现在这个不行 查看更多
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