求助2,2,2-三氟-N-苯基亚氨代乙酰氯合成问题？ 产物沸点 你查过吗， 这么低？看看这个文献如何？ seven grams (37.0 mmol) of 2,2,2-trifluoro-n-phenylacetamide, 19.84 g (74.0 mmol) of diphenyl chlorophosphate, 7.44 g (74.0 mmol) of triethylamine, and 28 ml of acetonitrile were introduced into a 100 ml flask and reacted for 15 hours while being refluxed (82.deg.c). after the reaction, the reaction solution was cooled to room temperature, 28 ml of ethyl acetate was added thereto, and the precipitate was then filtered off. the filtrate was subjected to solvent removal by evaporation, and the crude product thus obtained was purified by column chromatography (silica gel, ethyl acetate:hexane = 3:7), resulting in 6.24 g of n-phenyl-2,2,2-trifluoroacetimidoyl chloride as a yellow liquid (yield: 81.2percent). 查看更多
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