河南煤合成气发酵制乙醇的项目进展如何? synthetic biology for high-value chemicals lanzatech’s proprietary microbe is naturally occurring and is categorised as a who-risk 1 organism (same as baker’s yeast). the microbe acts a biocatalyst which allows production of both fuels and chemicals from industrial waste gases. lanzatech is the first company to develop a bio-catalytic toolkit for a gas fermentation microbe through which we have been able to: • secure multiple proprietary genomes • construct a detailed gene expression database • establish our proprietary synthetic biology platform • develop a plug-and-play gene expression/gene regulation system these advancements will allow us to move beyond ethanol and 2,3bd production to other fuels and chemicals (e.g., isoprene, mek, isopropanol,etc.), which serve as the building blocks for products such as diesel, jet fuel, olefins, and plastics. 简单看了下网页，貌似技术走的是构建工程菌，合成生物学的途径，也就是生物发酵的技术。 目前合成气发酵这个好像是个新的技术，不过貌似不热，主要是因为和普通用淀粉或者葡萄糖发酵“换汤不换药”，底物变成了合成气。 个人的一点观点：目前能够利用合成气的微生物主要是梭菌，但梭菌不产乙醇啊，所以要用到基因工程的方法，但据我所知，梭菌代谢机理较复杂，分子操作较难，即使是很成熟的丙丁梭菌发酵，也主要是利用天然菌的发酵，工程菌改进这块paper不少，专利不少，工业化貌似没有。 另外即使能够产乙醇，效率肯定高不到哪儿去，分离成本上要增加了，肯定不如传统的酵母产乙醇有竞争力。 总之该项目钻了个个空子：利用工业废气。查看更多
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