求教水解方法？ 看看这个.希望对你有用. to a solution of nitrile 1 (10 mmol) in a mixture acetoneacetone- water 1:l (15 ml), there are added uhp (40 mmol) and anhydrous potassium carbonate (0.14 g). the resulting suspension is stirred at room temperature for 0.5-2.5 h (see table). after completion of the reaction, acetone is removed under vacuum. depending on the solubility of amides, one of the following isolation procedures is used: (a) for water soluble amides (entries 1,3,4,7,8,11-15)t he residue is extracted with dichloromethane, the organic layer dried (mgso ) and concentrated to give crude product; (b) for water insoluble amides (entries 2,5,6,9,10) water (10 ml) is added to the residue, the product filtered off, washed with water and dried. 如果要原文,留个电子邮箱 查看更多
第1天
关注盖德视界
添加小助手
