如何充分利用TRANSFAC中的数据, 并且要把假阳性降至可以接受的程度?well if you are unhappy about the assumption for site independency in a simple position specific scoring matrix (PSSM), you can go to use high-order descriptions such as high-order HMM.In principle, I think the technique of motif minding has been quite mature. There might be some developments in new techniques, but I doubt there will be any huge breakthroughs. I think more oppunties lie in the use of new types of data. For example, Richard Young's Chip-Chip data turn out to be very stimulating for new advances in TF analyses. With AS, future chances shoud lie in the mining of splicing microarray data, which are coming out at a very impressive speed during the past 1-2 years. 查看更多
复方降脂药“葆至能”在中国上市?依折麦布/辛伐他汀联合用药疗效和安全性优于阿托伐他汀(VYTELD研究) Safety and Efficacy of Ezetimibe/Simvastatin Combination Versus Atorvastatin Alone in Adults 65 Years of Age With Hypercholesterolemia and With or at Moderately High/High Risk for Coronary Heart Disease(the VYTELD Study)查看更多