镍催化剂的制备？ 购买 不是太贵啊，说不定合成成本也这个价格http:///chem ... ty_cn_cb3416370.htm‘wiki 中就有啊 ，http:///wiki/dic ... hino)propane)nickel里面的第一篇文献。preparationnicl2(dppp) is prepared by combining equal molar portions of nickel(ii) chloride hexahydrate with 1,3-bis(diphenylphosphino)propane in 2-propanol.[1]ni(h2o)6cl2 + dppp → nicl2(dppp) + 6 h2o[edit]reactionsit is used in grignard reagent reactions involving cross-coupling of aryl halides, converting enol ethers, dithioacetals, and vinyl sulfides to olefins. nicl2(dppp) is used because the douple phosphate ligand minimizes the reduction reactions with labile β-hydrogens. [2]cross-coupling reactions of r-x compounds with organometallic nucleophiles are catalyzed by transition metal complexes such as nicl2(dppp). the r group consists of aryl, vinyl, or allyl groups and the x group is a good leaving group. cross-coupling reactions are effective at producing carbon-carbon bonds. catalysts that have bidentate phosphine ligands serve as the best catalysts.[3]nicl2(dppp) serves as the catalyst by bonding the two cross-coupling components to the nickel. the cross-coupling proceeds by oxidative addition of the aryl, vinyl, or allyl halide to nicl2(dppp) forming an oxidative addition adduct, r1-nicl(dppp). the organometallic nucleophile, r2-mgbr, reacts with r1-nicl(dppp) and is followed by the cross-coupling reaction producing the r1-r2 product. [4]the compound is a catalyst for kumada coupling reactions involving alkyl, alkenyl, aryl, and heteroaryl grignard reagents with aryl, heteroaryl, and alkenyl halides. [1][edit]references^ a b kumada, makota; tamao, kohei; sumitani, koji (1988), "phosphine-nickel complex catalyzed cross-coupling of grignard reagents with aryl and alkenyl halides: 1,2-dibutylbenzene", org. synth.; coll. vol. 6: 407， 查看更多
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