液质联用外标法相关问题?用外标法的话要尽可能通过前处理减弱基质效应。确定方法后,通过实际样品所得的标曲与标准品所得标曲的斜率比值得到矫正后的基质效应的参数,实际样品测定的含量需要这个矫正参数转换成基质中该物质的实际含量Calibration curve slope ratios (matrix matched to pure solvent) were calculated to determine the matrix effects resulting in signal enhancement suppression Signal enhancement occurs if the ratio of the slopes is larger than 100%. If the ratio isless than 100%, it is the indication of signal suppression. According to previous report, a strong matrix effect occurred when the ratios were below 50% or above 150%, and a medium matrix effect would be between 50% and 80% or between 120% and 150%. A ratio between 80% and 120% was considered as no matrix effect, because this variation is close to the repeatable values.这类分析方法文献中都用提到,LZ可以看下分析类的这方面文献,查看更多