如何避免高压釜氮气吹扫带走低沸点底物？A 2-mL vial with a magnetic stirring bar was charged with ligand 1 (0.6 ímol in 0.2 mL of toluene) and Rh(acac)(CO)2 (0.2 ímol in 0.2 mL of 1 mM toluene) under air. The mixture was stirred for 5 min. 1-Octene (2 mmol) was then added, followed by decane (0.1 mL) as internal standard. Additional toluene was added to bring the total reaction volume to 1 mL. The reaction mixture was transferred to an autoclave. The autoclave was purged with nitrogen three times and subsequently charged with CO (10 bar) and H2 (10 bar). The autoclave was then heated to 80 °C (oil bath). After 1 h, the autoclave was cooled in icy water, and the pressure was carefully released in a well-ventilated hood. The reaction mixture was immediately analyzed by GC. 关于上面的氢甲酰化实验操作中：“The autoclave was purged with nitrogen three times”，这个具体是怎么操作的？从进气口充进去N2（例如5atm），然后再从排气口排掉？不担心120度沸点的1-octene被带走吗？ 如果用更为低沸点的底物（例如1- 己烯 ，沸点60度），如果也如此操作，大部分的底物不会被 氮气 吹走吗？ 另外，排气过程（从20bar泄压）也会带走很多底物吧，这样会不会导致烯烃损失？ 如果想尽量避免低沸点底物损失，在置换气过程和排气过程应该如何操作 高压釜 ？ 200金币求教高压釜有高手解答，感激不尽！查看更多2个回答 . 15人已关注
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