谁能查默克索引，帮查一下。cas:846589？Monograph number: 10424 Title: Lorcaserin CAS Registry Number: 616202-92-7 CAS Name: (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine Molecular Formula: C11H14ClN Molecular Weight: 195.69 Percent Composition: C 67.51%, H 7.21%, Cl 18.12%, N 7.16% Literature References: Serotonin 5-HT2c receptor agonist. Prepn: J. Smith, B. Smith, WO 03086306; eidem, US 6953787 (2003, 2005 both to Arena); B. M. Smith et al. J. Med. Chem. 51, 305 (2008) DOI PMID . Pharmacology and receptor binding: W. J. Thomsen et al., J. Pharmacol. Exp. Ther. 325, 577 (2008) DOI PMID . Clinical trial for weight management in obese patients: S. R. Smith et al., N. Engl. J. Med. 363, 245 (2010) DOI PMID . Derivative Type: Hydrochloride CAS Registry Number: 846589-98-8 Manufacturers' Codes: APD-356 Trademarks: Lorqess (Arena) Molecular Formula: C11H14ClN.HCl Molecular Weight: 232.15 Percent Composition: C 56.91%, H 6.51%, Cl 30.54%, N 6.03% Literature References: Prepn: R. K. Agarwal et al., WO 06069363 (2006 to Arena). Properties: Hygroscopic crystals, mp 201°. Readily converts to a crystalline hemihydrate.查看更多
第1天
关注盖德视界
添加小助手
